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Denovo designing, retro-combinatorial synthesis, and molecular dynamics analysis identify novel antiviral VTRM1.1 against RNA-dependent RNA polymerase of SARS CoV2 virus
A novel coronavirus disease (COVID-19) caused by SARS-CoV2 has now spread globally. Replication/transcription machinery of this virus consists of RNA-dependent RNA polymerase (nsp12 or RdRp) and its two cofactors nsp7 and nsp8 proteins. Hence, RdRp has emerged as a promising target to control COVID-...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier B.V.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787912/ https://www.ncbi.nlm.nih.gov/pubmed/33421473 http://dx.doi.org/10.1016/j.ijbiomac.2020.12.223 |