Adeno-associated virus-mediated delivery of anti-miR-199a tough decoys attenuates cardiac hypertrophy by targeting PGC-1alpha

MicroRNAs (miRNAs) are important regulators in the process of cardiac hypertrophy and heart failure. Previous studies have shown that miR-199a is upregulated in pressure-overload cardiac hypertrophy and that inhibition of miR-199a attenuates cardiac hypertrophy in vitro. However, the therapeutic rol...

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Detalles Bibliográficos
Autores principales: Yan, Hualin, Wang, Hong, Zhu, Xiaoxia, Huang, Jianbo, Li, Yifei, Zhou, Kaiyu, Hua, Yimin, Yan, Feng, Wang, Da-Zhi, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787996/
https://www.ncbi.nlm.nih.gov/pubmed/33473326
http://dx.doi.org/10.1016/j.omtn.2020.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787996/
https://www.ncbi.nlm.nih.gov/pubmed/33473326
http://dx.doi.org/10.1016/j.omtn.2020.11.007

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