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Adeno-associated virus-mediated delivery of anti-miR-199a tough decoys attenuates cardiac hypertrophy by targeting PGC-1alpha

MicroRNAs (miRNAs) are important regulators in the process of cardiac hypertrophy and heart failure. Previous studies have shown that miR-199a is upregulated in pressure-overload cardiac hypertrophy and that inhibition of miR-199a attenuates cardiac hypertrophy in vitro. However, the therapeutic rol...

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Detalles Bibliográficos
Autores principales:	Yan, Hualin, Wang, Hong, Zhu, Xiaoxia, Huang, Jianbo, Li, Yifei, Zhou, Kaiyu, Hua, Yimin, Yan, Feng, Wang, Da-Zhi, Luo, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787996/ https://www.ncbi.nlm.nih.gov/pubmed/33473326 http://dx.doi.org/10.1016/j.omtn.2020.11.007

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