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Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

OBJECTIVES: Systemic lupus erythematosus (SLE) is an autoimmune disease with extensive heterogeneity in disease presentation between patients, which is likely due to an underlying molecular diversity. Here, we aimed at elucidating the genetic aetiology of SLE from the immunity pathway level to the s...

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Detalles Bibliográficos
Autores principales: Sandling, Johanna K, Pucholt, Pascal, Hultin Rosenberg, Lina, Farias, Fabiana H G, Kozyrev, Sergey V, Eloranta, Maija-Leena, Alexsson, Andrei, Bianchi, Matteo, Padyukov, Leonid, Bengtsson, Christine, Jonsson, Roland, Omdal, Roald, Lie, Benedicte A, Massarenti, Laura, Steffensen, Rudi, Jakobsen, Marianne A, Lillevang, Søren T, Lerang, Karoline, Molberg, Øyvind, Voss, Anne, Troldborg, Anne, Jacobsen, Søren, Syvänen, Ann-Christine, Jönsen, Andreas, Gunnarsson, Iva, Svenungsson, Elisabet, Rantapää-Dahlqvist, Solbritt, Bengtsson, Anders A, Sjöwall, Christopher, Leonard, Dag, Lindblad-Toh, Kerstin, Rönnblom, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788061/
https://www.ncbi.nlm.nih.gov/pubmed/33037003
http://dx.doi.org/10.1136/annrheumdis-2020-218636