Tryptanthrin from microwave-assisted reduction of isatin using solid-state-supported sodium borohydride: DFT calculations, molecular docking and evaluation of its analgesic and anti-inflammatory activity

Tryptanthrin is a potent natural alkaloid with good in vitro pharmacological properties. Herein, we report the synthesis of the compound via a new method involving the reduction of isatin with solid-state-supported sodium borohydride under microwave irradiation. The title compound has been tested fo...

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Detalles Bibliográficos
Autores principales: Obafemi, Craig A., Adegbite, Oluwaseun B., Fadare, Olatomide A., Iwalewa, Ezekiel O., Omisore, Nusrat O., Sanusi, Kayode, Yilmaz, Yusuf, Ceylan, Ümit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788106/
https://www.ncbi.nlm.nih.gov/pubmed/33437886
http://dx.doi.org/10.1016/j.heliyon.2020.e05756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788106/
https://www.ncbi.nlm.nih.gov/pubmed/33437886
http://dx.doi.org/10.1016/j.heliyon.2020.e05756

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