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RhoA GTPase phosphorylated at tyrosine 42 by src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A

In the Wnt canonical pathway, Wnt3A has been known to stabilize β-catenin. In the non-canonical Wnt signaling pathway, Wnt is known to activate Rho GTPases. The correlation between canonical and non-canonical pathways by Wnt signaling, however, has not been well elucidated. Here, we identified that...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Gyu, Mahmud, Shohel, Min, Jung Ki, Lee, Yoon-Beom, Kim, Hyunbin, Kang, Dong-Chul, Park, Hwee-Seon, Seong, Jihye, Park, Jae-Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788234/
https://www.ncbi.nlm.nih.gov/pubmed/33388549
http://dx.doi.org/10.1016/j.redox.2020.101842