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Chaperones and Ubiquitin Ligases Balance Mutant p53 Protein Stability in Esophageal and Other Digestive Cancers

The incidence of esophageal adenocarcinoma (EAC) and other gastrointestinal (GI) cancers have risen dramatically, thus defining the oncogenic drivers to develop effective therapies are necessary. Patients with Barrett’s Esophagus (BE), have an elevated risk of developing EAC. Around 70%–80% of BE ca...

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Detalles Bibliográficos
Autores principales: Martinho, May San, Nancarrow, Derek J., Lawrence, Theodore S., Beer, David G., Ray, Dipankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788241/
https://www.ncbi.nlm.nih.gov/pubmed/33130332
http://dx.doi.org/10.1016/j.jcmgh.2020.10.012