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Tnfaip2/exoc3‐driven lipid metabolism is essential for stem cell differentiation and organ homeostasis

Lipid metabolism influences stem cell maintenance and differentiation but genetic factors that control these processes remain to be delineated. Here, we identify Tnfaip2 as an inhibitor of reprogramming of mouse fibroblasts into induced pluripotent stem cells. Tnfaip2 knockout impairs differentiatio...

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Detalles Bibliográficos
Autores principales: Deb, Sarmistha, Felix, Daniel A, Koch, Philipp, Deb, Maharshi Krishna, Szafranski, Karol, Buder, Katrin, Sannai, Mara, Groth, Marco, Kirkpatrick, Joanna, Pietsch, Stefan, Gollowitzer, André, Groß, Alexander, Riemenschneider, Philip, Koeberle, Andreas, González‐Estévez, Cristina, Rudolph, Karl Lenhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788457/
https://www.ncbi.nlm.nih.gov/pubmed/33300287
http://dx.doi.org/10.15252/embr.201949328