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Tnfaip2/exoc3‐driven lipid metabolism is essential for stem cell differentiation and organ homeostasis
Lipid metabolism influences stem cell maintenance and differentiation but genetic factors that control these processes remain to be delineated. Here, we identify Tnfaip2 as an inhibitor of reprogramming of mouse fibroblasts into induced pluripotent stem cells. Tnfaip2 knockout impairs differentiatio...
Autores principales: | Deb, Sarmistha, Felix, Daniel A, Koch, Philipp, Deb, Maharshi Krishna, Szafranski, Karol, Buder, Katrin, Sannai, Mara, Groth, Marco, Kirkpatrick, Joanna, Pietsch, Stefan, Gollowitzer, André, Groß, Alexander, Riemenschneider, Philip, Koeberle, Andreas, González‐Estévez, Cristina, Rudolph, Karl Lenhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788457/ https://www.ncbi.nlm.nih.gov/pubmed/33300287 http://dx.doi.org/10.15252/embr.201949328 |
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