Modeling drug mechanism of action with large scale gene-expression profiles using GPAR, an artificial intelligence platform

BACKGROUND: Querying drug-induced gene expression profiles with machine learning method is an effective way for revealing drug mechanism of actions (MOAs), which is strongly supported by the growth of large scale and high-throughput gene expression databases. However, due to the lack of code-free an...

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Detalles Bibliográficos
Autores principales: Gao, Shengqiao, Han, Lu, Luo, Dan, Liu, Gang, Xiao, Zhiyong, Shan, Guangcun, Zhang, Yongxiang, Zhou, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788535/
https://www.ncbi.nlm.nih.gov/pubmed/33413089
http://dx.doi.org/10.1186/s12859-020-03915-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788535/
https://www.ncbi.nlm.nih.gov/pubmed/33413089
http://dx.doi.org/10.1186/s12859-020-03915-6

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