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Modeling drug mechanism of action with large scale gene-expression profiles using GPAR, an artificial intelligence platform
BACKGROUND: Querying drug-induced gene expression profiles with machine learning method is an effective way for revealing drug mechanism of actions (MOAs), which is strongly supported by the growth of large scale and high-throughput gene expression databases. However, due to the lack of code-free an...
Autores principales: | Gao, Shengqiao, Han, Lu, Luo, Dan, Liu, Gang, Xiao, Zhiyong, Shan, Guangcun, Zhang, Yongxiang, Zhou, Wenxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788535/ https://www.ncbi.nlm.nih.gov/pubmed/33413089 http://dx.doi.org/10.1186/s12859-020-03915-6 |
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