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Comparison of Amorphous Solid Dispersions of Spironolactone Prepared by Spray Drying and Electrospinning: The Influence of the Preparation Method on the Dissolution Properties

[Image: see text] This research aimed to compare two solvent-based methods for the preparation of amorphous solid dispersions (ASDs) made up of poorly soluble spironolactone and poly(vinylpyrrolidone-co-vinyl acetate). The same apparatus was used to produce, in continuous mode, drug-loaded electrosp...

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Detalles Bibliográficos
Autores principales: Szabó, Edina, Záhonyi, Petra, Brecska, Dániel, Galata, Dorián L., Mészáros, Lilla A., Madarász, Lajos, Csorba, Kristóf, Vass, Panna, Hirsch, Edit, Szafraniec-Szczęsny, Joanna, Csontos, István, Farkas, Attila, Van denMooter, Guy, Nagy, Zsombor K., Marosi, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788570/
https://www.ncbi.nlm.nih.gov/pubmed/33301326
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00965