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Comparison of Amorphous Solid Dispersions of Spironolactone Prepared by Spray Drying and Electrospinning: The Influence of the Preparation Method on the Dissolution Properties
[Image: see text] This research aimed to compare two solvent-based methods for the preparation of amorphous solid dispersions (ASDs) made up of poorly soluble spironolactone and poly(vinylpyrrolidone-co-vinyl acetate). The same apparatus was used to produce, in continuous mode, drug-loaded electrosp...
Autores principales: | Szabó, Edina, Záhonyi, Petra, Brecska, Dániel, Galata, Dorián L., Mészáros, Lilla A., Madarász, Lajos, Csorba, Kristóf, Vass, Panna, Hirsch, Edit, Szafraniec-Szczęsny, Joanna, Csontos, István, Farkas, Attila, Van denMooter, Guy, Nagy, Zsombor K., Marosi, György |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788570/ https://www.ncbi.nlm.nih.gov/pubmed/33301326 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00965 |
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