miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein

BACKGROUND: FMRP is a selective mRNA-binding protein that regulates protein synthesis at synapses, and its loss may lead to the impairment of trace fear memory. Previously, we found that FMRP levels in the hippocampus of rats with post-traumatic stress disorder (PTSD) were decreased. However, the me...

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Detalles Bibliográficos
Autores principales: Nie, Peng-Yin, Tong, Lei, Li, Ming-Da, Fu, Chang-Hai, Peng, Jun-Bo, Ji, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788709/
https://www.ncbi.nlm.nih.gov/pubmed/33407653
http://dx.doi.org/10.1186/s12974-020-02064-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788709/
https://www.ncbi.nlm.nih.gov/pubmed/33407653
http://dx.doi.org/10.1186/s12974-020-02064-0

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