Pharmacokinetic profile of amodiaquine and its active metabolite desethylamodiaquine in Ghanaian patients with uncomplicated falciparum malaria

BACKGROUND: Accurate measurement of anti-malarial drug concentrations in therapeutic efficacy studies is essential to distinguish between inadequate drug exposure and anti-malarial drug resistance, and to inform optimal anti-malarial dosing in key target population groups. METHODS: A sensitive and s...

Descripción completa

Detalles Bibliográficos
Autores principales: Anyorigiya, Thomas A., Castel, Sandra, Mauff, Katya, Atuguba, Frank, Ogutu, Bernhards, Oduro, Abraham, Dosoo, David, Asante, Kwaku-Poku, Owusu-Agyei, Seth, Dodoo, Alexander, Hodgson, Abraham, Binka, Fred, Workman, Lesley J., Allen, Elizabeth N., Denti, Paolo, Wiesner, Lubbe, Barnes, Karen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788723/
https://www.ncbi.nlm.nih.gov/pubmed/33407454
http://dx.doi.org/10.1186/s12936-020-03553-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788723/
https://www.ncbi.nlm.nih.gov/pubmed/33407454
http://dx.doi.org/10.1186/s12936-020-03553-6

Ejemplares similares