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Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer

BACKGROUND: The H&E stromal tumor-infiltrating lymphocyte (sTIL) score and programmed death ligand 1 (PD-L1) SP142 immunohistochemistry assay are prognostic and predictive in early-stage breast cancer, but are operator-dependent and may have insufficient precision to characterize dynamic changes...

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Detalles Bibliográficos
Autores principales: Sanchez, Katherine, Kim, Isaac, Chun, Brie, Pucilowska, Joanna, Redmond, William L., Urba, Walter J., Martel, Maritza, Wu, Yaping, Campbell, Mary, Sun, Zhaoyu, Grunkemeier, Gary, Chang, Shu Ching, Bernard, Brady, Page, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788790/
https://www.ncbi.nlm.nih.gov/pubmed/33413574
http://dx.doi.org/10.1186/s13058-020-01378-4