An interpretable bimodal neural network characterizes the sequence and preexisting chromatin predictors of induced transcription factor binding

BACKGROUND: Transcription factor (TF) binding specificity is determined via a complex interplay between the transcription factor’s DNA binding preference and cell type-specific chromatin environments. The chromatin features that correlate with transcription factor binding in a given cell type have b...

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Detalles Bibliográficos
Autores principales: Srivastava, Divyanshi, Aydin, Begüm, Mazzoni, Esteban O., Mahony, Shaun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788824/
https://www.ncbi.nlm.nih.gov/pubmed/33413545
http://dx.doi.org/10.1186/s13059-020-02218-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788824/
https://www.ncbi.nlm.nih.gov/pubmed/33413545
http://dx.doi.org/10.1186/s13059-020-02218-6

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