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An interpretable bimodal neural network characterizes the sequence and preexisting chromatin predictors of induced transcription factor binding
BACKGROUND: Transcription factor (TF) binding specificity is determined via a complex interplay between the transcription factor’s DNA binding preference and cell type-specific chromatin environments. The chromatin features that correlate with transcription factor binding in a given cell type have b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788824/ https://www.ncbi.nlm.nih.gov/pubmed/33413545 http://dx.doi.org/10.1186/s13059-020-02218-6 |