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MCCC2 promotes HCC development by supporting leucine oncogenic function

BACKGROUND: The role of methylcrotonoyl-CoA carboxylase 2 (MCCC2) in the development of tumors is well-established, and the involvement of leucine in the liver is well-known. However, the role of MCCC2 and the correlation between MCCC2 and leucine in the progression of hepatocellular carcinoma (HCC)...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Yan, Zhang, Xue-Ning, Xu, Chen-Zhou, Zhou, Dan-Hua, Chen, Jing, Liu, Zhao-Xiu, sun, Ying, Huang, Wei, Qu, Li-Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788835/
https://www.ncbi.nlm.nih.gov/pubmed/33407468
http://dx.doi.org/10.1186/s12935-020-01722-w