HapSolo: an optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding

BACKGROUND: Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not properly id...

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Detalles Bibliográficos
Autores principales: Solares, Edwin A., Tao, Yuan, Long, Anthony D., Gaut, Brandon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788845/
https://www.ncbi.nlm.nih.gov/pubmed/33407090
http://dx.doi.org/10.1186/s12859-020-03939-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788845/
https://www.ncbi.nlm.nih.gov/pubmed/33407090
http://dx.doi.org/10.1186/s12859-020-03939-y

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