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HapSolo: an optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding
BACKGROUND: Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not properly id...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788845/ https://www.ncbi.nlm.nih.gov/pubmed/33407090 http://dx.doi.org/10.1186/s12859-020-03939-y |