SCC: an accurate imputation method for scRNA-seq dropouts based on a mixture model

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) enables the possibility of many in-depth transcriptomic analyses at a single-cell resolution. It’s already widely used for exploring the dynamic development process of life, studying the gene regulation mechanism, and discovering new cell types. How...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Yan, Zhong, Yuanke, Hu, Jialu, Shang, Xuequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788948/
https://www.ncbi.nlm.nih.gov/pubmed/33407064
http://dx.doi.org/10.1186/s12859-020-03878-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788948/
https://www.ncbi.nlm.nih.gov/pubmed/33407064
http://dx.doi.org/10.1186/s12859-020-03878-8

Ejemplares similares