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SCC: an accurate imputation method for scRNA-seq dropouts based on a mixture model

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) enables the possibility of many in-depth transcriptomic analyses at a single-cell resolution. It’s already widely used for exploring the dynamic development process of life, studying the gene regulation mechanism, and discovering new cell types. How...

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Detalles Bibliográficos
Autores principales:	Zheng, Yan, Zhong, Yuanke, Hu, Jialu, Shang, Xuequn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788948/ https://www.ncbi.nlm.nih.gov/pubmed/33407064 http://dx.doi.org/10.1186/s12859-020-03878-8

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