Connecting the αα-hubs: same fold, disordered ligands, new functions

BACKGROUND: Signal fidelity depends on protein–protein interaction–‘hubs’ integrating cues from large interactomes. Recently, and based on a common secondary structure motif, the αα-hubs were defined, which are small α-helical domains of large, modular proteins binding intrinsically disordered trans...

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Detalles Bibliográficos
Autores principales: Staby, Lasse, Bugge, Katrine, Falbe-Hansen, Rasmus Greve, Salladini, Edoardo, Skriver, Karen, Kragelund, Birthe B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788954/
https://www.ncbi.nlm.nih.gov/pubmed/33407551
http://dx.doi.org/10.1186/s12964-020-00686-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788954/
https://www.ncbi.nlm.nih.gov/pubmed/33407551
http://dx.doi.org/10.1186/s12964-020-00686-8

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