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Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function
BACKGROUND: Due to their much lower costs in experiment and computation than metagenomic whole-genome sequencing (WGS), 16S rRNA gene amplicons have been widely used for predicting the functional profiles of microbiome, via software tools such as PICRUSt 2. However, due to the potential PCR bias and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7788972/ https://www.ncbi.nlm.nih.gov/pubmed/33407112 http://dx.doi.org/10.1186/s12864-020-07307-1 |