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Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma

BACKGROUND: The development of novel and effective drugs for targeted human hepatocellular carcinoma still remains a great challenge. The alkaloid nitidine chloride (NC), a component of a traditional Chinese medicine, has been shown to have anticancer properties, but doses at therapeutic levels have...

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Detalles Bibliográficos
Autores principales: Li, Danni, Liu, Shaogang, Zhu, Jiahao, Shen, Liqun, Zhang, Qi ying, Zhu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789002/
https://www.ncbi.nlm.nih.gov/pubmed/33407916
http://dx.doi.org/10.1186/s40360-020-00461-y