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OxLDL/β2GPI/anti-β2GPI Ab complex induces inflammatory activation via the TLR4/NF-κB pathway in HUVECs

Patients with antiphospholipid syndrome have been identified to have higher incidence rates of atherosclerosis (AS) due to the elevated levels of anti-β2-glycoprotein I (β2GPI) antibody (Ab). Our previous studies revealed that the anti-β2GPI Ab formed a stable oxidized low-density lipoprotein (oxLDL...

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Detalles Bibliográficos
Autores principales: Zhang, Guiting, Cai, Qianqian, Zhou, Hong, He, Chao, Chen, Yudan, Zhang, Peng, Wang, Ting, Xu, Liangjie, Yan, Jinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789093/
https://www.ncbi.nlm.nih.gov/pubmed/33355374
http://dx.doi.org/10.3892/mmr.2020.11787