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Liraglutide protects palmitate-induced INS-1 cell injury by enhancing autophagy mediated via FoxO1
Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance and a progressive loss in mass and function of pancreatic β-cells. In T2DM, lipotoxicity leads to β-cells dysfunction and decreases its number. Autophagy serves a crucial role in maintaining the normal islet architecture and the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789139/ https://www.ncbi.nlm.nih.gov/pubmed/33355375 http://dx.doi.org/10.3892/mmr.2020.11786 |