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The intranasal dexmedetomidine plus ketamine for procedural sedation in children, adaptive randomized controlled non-inferiority multicenter trial (Ketodex): a statistical analysis plan

BACKGROUND: Procedural sedation and analgesia (PSA) is frequently required to perform closed reductions for fractures and dislocations in children. Intravenous (IV) ketamine is the most commonly used sedative agent for closed reductions. However, as children find IV insertion a distressing and painf...

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Detalles Bibliográficos
Autores principales: Heath, Anna, Rios, Juan David, Pullenayegum, Eleanor, Pechlivanoglou, Petros, Offringa, Martin, Yaskina, Maryna, Watts, Rick, Rimmer, Shana, Klassen, Terry P., Coriolano, Kamary, Poonai, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789159/
https://www.ncbi.nlm.nih.gov/pubmed/33407719
http://dx.doi.org/10.1186/s13063-020-04946-3