A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma

BACKGROUND: The tumor immunological microenvironment (TIME) has a prominent impact on prognosis and immunotherapy. However, the heterogeneous TIME and the mechanisms by which TIME affects immunotherapy have not been elucidated in hepatocellular carcinoma (HCC). METHODS: A total of 2195 eligible HCC...

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Detalles Bibliográficos
Autores principales: Liu, Zaoqu, Zhang, Yuyuan, Shi, Chengcheng, Zhou, Xueliang, Xu, Kaihao, Jiao, Dechao, Sun, Zhenqiang, Han, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789239/
https://www.ncbi.nlm.nih.gov/pubmed/33407585
http://dx.doi.org/10.1186/s12967-020-02697-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789239/
https://www.ncbi.nlm.nih.gov/pubmed/33407585
http://dx.doi.org/10.1186/s12967-020-02697-y

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