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A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma
BACKGROUND: The tumor immunological microenvironment (TIME) has a prominent impact on prognosis and immunotherapy. However, the heterogeneous TIME and the mechanisms by which TIME affects immunotherapy have not been elucidated in hepatocellular carcinoma (HCC). METHODS: A total of 2195 eligible HCC...
Autores principales: | Liu, Zaoqu, Zhang, Yuyuan, Shi, Chengcheng, Zhou, Xueliang, Xu, Kaihao, Jiao, Dechao, Sun, Zhenqiang, Han, Xinwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789239/ https://www.ncbi.nlm.nih.gov/pubmed/33407585 http://dx.doi.org/10.1186/s12967-020-02697-y |
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