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Sialylated human milk oligosaccharides prevent intestinal inflammation by inhibiting toll like receptor 4/NLRP3 inflammasome pathway in necrotizing enterocolitis rats

BACKGROUND: Necrotizing enterocolitis (NEC) remains a fatal gastrointestinal disorder in neonates and has very limited therapeutic options. Sialylated human milk oligosaccharides (SHMOs) improve pathological changes in experimental NEC models. The objectives of this study were to investigate the inv...

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Detalles Bibliográficos
Autores principales: Zhang, Wenting, He-Yang, Jingqiu, Tu, Wenjuan, Zhou, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789326/
https://www.ncbi.nlm.nih.gov/pubmed/33407596
http://dx.doi.org/10.1186/s12986-020-00534-z