Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-onset neurodegenerative diseases that affect the motor and cognitive functions, respectively. Multiple common genetic loci such as fused in sarcoma (FUS) have been identifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Wan Yun, Agrawal, Ira, Tyan, Sheue-Houy, Sanford, Emma, Chang, Wei-Tang, Lim, Kenneth, Ong, Jolynn, Tan, Bernice Siu Yan, Moe, Aung Aung Kywe, Yu, Regina, Wong, Peiyan, Tucker-Kellogg, Greg, Koo, Edward, Chuang, Kai-Hsiang, Ling, Shuo-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789430/
https://www.ncbi.nlm.nih.gov/pubmed/33407930
http://dx.doi.org/10.1186/s40478-020-01111-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789430/
https://www.ncbi.nlm.nih.gov/pubmed/33407930
http://dx.doi.org/10.1186/s40478-020-01111-4

Ejemplares similares