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Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-onset neurodegenerative diseases that affect the motor and cognitive functions, respectively. Multiple common genetic loci such as fused in sarcoma (FUS) have been identifie...

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Detalles Bibliográficos
Autores principales:	Ho, Wan Yun, Agrawal, Ira, Tyan, Sheue-Houy, Sanford, Emma, Chang, Wei-Tang, Lim, Kenneth, Ong, Jolynn, Tan, Bernice Siu Yan, Moe, Aung Aung Kywe, Yu, Regina, Wong, Peiyan, Tucker-Kellogg, Greg, Koo, Edward, Chuang, Kai-Hsiang, Ling, Shuo-Chien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789430/ https://www.ncbi.nlm.nih.gov/pubmed/33407930 http://dx.doi.org/10.1186/s40478-020-01111-4

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