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Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology

BACKGROUND: Spinal cord injury (SCI) presents a significant challenge for the field of neurotherapeutics. Stem cells have shown promise in replenishing the cells lost to the injury process, but the release of axon growth-inhibitory molecules such as chondroitin sulfate proteoglycans (CSPGs) by activ...

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Detalles Bibliográficos
Autores principales: Jevans, Benjamin, James, Nicholas D., Burnside, Emily, McCann, Conor J., Thapar, Nikhil, Bradbury, Elizabeth J., Burns, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789480/
https://www.ncbi.nlm.nih.gov/pubmed/33407795
http://dx.doi.org/10.1186/s13287-020-02031-9