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Connective tissue remodelling is differently modulated by tocilizumab versus methotrexate monotherapy in patients with early rheumatoid arthritis: the AMBITION study

OBJECTIVE: Associations between rheumatoid arthritis (RA) and effect of treatment at the tissue levels are poorly understood. We investigated the scope of released extracellular matrix (ECM) metabolites as a consequence of tissue remodelling in patients treated with methotrexate (MTX) and tocilizuma...

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Detalles Bibliográficos
Autores principales: Drobinski, Patryk J., Bay-Jensen, Anne C., Karsdal, Morten A., Sardar, Samra, Siebuhr, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789531/
https://www.ncbi.nlm.nih.gov/pubmed/33413588
http://dx.doi.org/10.1186/s13075-020-02378-7