A novel long intergenic non-coding RNA, Nostrill, regulates iNOS gene transcription and neurotoxicity in microglia

BACKGROUND: Microglia are resident immunocompetent and phagocytic cells in the CNS. Pro-inflammatory microglia, stimulated by microbial signals such as bacterial lipopolysaccharide (LPS), viral RNAs, or inflammatory cytokines, are neurotoxic and associated with pathogenesis of several neurodegenerat...

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Detalles Bibliográficos
Autores principales: Mathy, Nicholas W., Burleigh, Olivia, Kochvar, Andrew, Whiteford, Erin R., Behrens, Matthew, Marta, Patrick, Tian, Cong, Gong, Ai-Yu, Drescher, Kristen M., Steyger, Peter S., Chen, Xian-Ming, Shibata, Annemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789650/
https://www.ncbi.nlm.nih.gov/pubmed/33407594
http://dx.doi.org/10.1186/s12974-020-02051-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789650/
https://www.ncbi.nlm.nih.gov/pubmed/33407594
http://dx.doi.org/10.1186/s12974-020-02051-5

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