Cargando…

Emodin regulates cell cycle of non-small lung cancer (NSCLC) cells through hyaluronan synthase 2 (HA2)-HA-CD44/receptor for hyaluronic acid-mediated motility (RHAMM) interaction-dependent signaling pathway

BACKGROUND: Non-small cell lung cancers (NSCLC) account for most cases of lung cancer. More effort is needed to research new drug and combination therapies for this disease. An anthraquinone derivative, emodin shows anticancer potency. We hypothesis that emodin suppresses lung cancer cells through h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Mingzhu, Jin, Shengbo, Cao, Yang, Xu, Jian, Zhu, Shendong, Li, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789699/ https://www.ncbi.nlm.nih.gov/pubmed/33407495 http://dx.doi.org/10.1186/s12935-020-01711-z

Ejemplares similares

Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase Impact Prostate Cancer Cell Behavior and Invadopodia Formation in 3D HA-Based Hydrogels
por: Gurski, Lisa A., et al.
Publicado: (2012)

Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells
por: Veiseh, Mandana, et al.
Publicado: (2015)

Hyaluronic Acid (HA) Receptors and the Motility of Schwann Cell(-Like) Phenotypes
por: Ouasti, Sihem, et al.
Publicado: (2020)

Hyaluronan (HA)-inspired glycopolymers as molecular tools for studying HA functions
por: Collis, Dominic W. P., et al.
Publicado: (2021)

The Impact of the Receptor of Hyaluronan-Mediated Motility (RHAMM) on Human Urothelial Transitional Cell Cancer of the Bladder
por: Niedworok, Christian, et al.
Publicado: (2013)

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer
por: Mele, Valentina, et al.
Publicado: (2017)

Understanding Hyaluronan Receptor (CD44) Interaction, HA-CD44 Activated Potential Targets in Cancer Therapeutics
por: Chaudhry, Gul-e-Saba, et al.
Publicado: (2021)

The Roles of Hyaluronan/RHAMM/CD44 and Their Respective Interactions along the Insidious Pathways of Fibrosarcoma Progression
por: Nikitovic, Dragana, et al.
Publicado: (2013)

Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer
por: Misra, Suniti, et al.
Publicado: (2015)

Phosphorylation of IGFBP-3 by Casein Kinase 2 Blocks Its Interaction with Hyaluronan, Enabling HA-CD44 Signaling Leading to Increased NSCLC Cell Survival and Cisplatin Resistance
por: Coleman, Kai-ling, et al.
Publicado: (2023)

TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan
Publicado: (1993)

Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling
por: Song, Jung Min, et al.
Publicado: (2017)

Hyaluronan and RHAMM in Wound Repair and the “Cancerization” of Stromal Tissues
por: Tolg, Cornelia, et al.
Publicado: (2014)

Hyaluronic Acid (Ha) Binding to Cd44 Activates Rac1 and Induces Lamellipodia Outgrowth
por: Oliferenko, Snezhana, et al.
Publicado: (2000)

Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity
Publicado: (1994)

Anti-Inflammatory Effects of the 35kDa Hyaluronic Acid Fragment (B-HA/HA35)
por: Jia, XiaoXiao, et al.
Publicado: (2023)

Use of Hyaluronic Acid (HA) in Chronic Airway Diseases
por: Máiz Carro, Luis, et al.
Publicado: (2020)

Effect of molecular weight of hyaluronic acid (HA) on viscoelasticity and particle texturing feel of HA dermal biphasic fillers
por: Chun, Cheolbyong, et al.
Publicado: (2016)

Editorial: Interaction Between Hyaluronic Acid and Its Receptors (CD44, RHAMM) Regulates the Activity of Inflammation and Cancer
por: Naor, David
Publicado: (2016)

In vitro analysis of the effects on wound healing of high- and low-molecular weight chains of hyaluronan and their hybrid H-HA/L-HA complexes
por: D’Agostino, Antonella, et al.
Publicado: (2015)

Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells
por: Marunaka, Kana, et al.
Publicado: (2021)

Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma
por: Wang, Dunrui, et al.
Publicado: (2016)

Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways
por: Saunders, Ian T., et al.
Publicado: (2019)

Soluble hyaluronan receptor RHAMM induces mitotic arrest by suppressing Cdc2 and cyclin B1 expression
Publicado: (1996)

Biological properties of influenza A virus mutants with amino acid substitutions in the HA2 glycoprotein of the HA1/HA2 interaction region
por: Jakubcová, L., et al.
Publicado: (2019)

Hyaluronic Acid (HA), Platelet-Rich Plasm and Extracorporeal Shock Wave Therapy (ESWT) promote human chondrocyte regeneration in vitro and ESWT-mediated increase of CD44 expression enhances their susceptibility to HA treatment
por: Vetrano, Mario, et al.
Publicado: (2019)

Pharmacological targeting transient receptor potential canonical channel 6 modulates biological behaviors for cervical cancer HeLa and SiHA cell
por: Bai, Li-ping, et al.
Publicado: (2022)

Abstract: In Vivo Degradation of Hyaluronic Acid (HA)-Based Fillers by Exogenous Hyaluronidases
por: Chopra, Raj, et al.
Publicado: (2016)

Synergistic Properties of Arabinogalactan (AG) and Hyaluronic Acid (HA) Sodium Salt Mixtures
por: Di Mola, Antonia, et al.
Publicado: (2021)

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer
por: Ying Zhi, Lu, et al.
Publicado: (2018)

Ha vuelto
por: Vermes, Timur
Publicado: (2013)

Efficient CD44-targeted magnetic resonance imaging (MRI) of breast cancer cells using hyaluronic acid (HA)-modified MnFe(2)O(4) nanocrystals
por: Lee, Taeksu, et al.
Publicado: (2013)

Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade
por: Miri, Seyed Mohammad, et al.
Publicado: (2020)

haXe 2 Beginner's Guide
por: Dasnois, Benjamin
Publicado: (2011)

Risk Comparison of Filler Embolism Between Polymethyl Methacrylate (PMMA) and Hyaluronic Acid (HA)
por: Nie, Fangfei, et al.
Publicado: (2019)

3D bioprinting of methacrylated hyaluronic acid (MeHA) hydrogel with intrinsic osteogenicity
por: Poldervaart, Michelle T., et al.
Publicado: (2017)

Morphological Effects of HA on the Cell Compatibility of Electrospun HA/PLGA Composite Nanofiber Scaffolds
por: Haider, Adnan, et al.
Publicado: (2014)

Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12) V-Ha-Ras transgenic mouse glioma model
por: Singh, Alok R, et al.
Publicado: (2014)

Comparison of Trehalose/Hyaluronic Acid (HA) vs. 0.001% Hydrocortisone/HA Eyedrops on Signs and Inflammatory Markers in a Desiccating Model of Dry Eye Disease (DED)
por: Astolfi, Gloria, et al.
Publicado: (2022)

Balancing Thymocyte Adhesion and Motility: A Functional Linkage Between β1 Lntegrins and The Motility Receptor RHAMM
por: Gares, Sheryl L., et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_t7j6nl9p56liuffqfvgfa7jira