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Targeting oncogenic Notch signaling with SERCA inhibitors

P-type ATPase inhibitors are among the most successful and widely prescribed therapeutics in modern pharmacology. Clinical transition has been safely achieved for H(+)/K(+) ATPase inhibitors such as omeprazole and Na(+)/K(+)-ATPase inhibitors like digoxin. However, this is more challenging for Ca(2+...

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Detalles Bibliográficos
Autores principales: Pagliaro, Luca, Marchesini, Matteo, Roti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789735/
https://www.ncbi.nlm.nih.gov/pubmed/33407740
http://dx.doi.org/10.1186/s13045-020-01015-9