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Exosomal LncRNA LINC00659 transferred from cancer-associated fibroblasts promotes colorectal cancer cell progression via miR-342-3p/ANXA2 axis

BACKGROUND: Cancer-associated fibroblasts (CAFs) play a pivotal role in regulating tumor progression by transferring exosomes to adjacent cells. Our aim was to clarify the role of LINC00659 encapsulated in CAFs-derived exosomes (CAFs-exo) in colorectal cancer (CRC). METHODS: CAFs and normal fibrobla...

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Detalles Bibliográficos
Autores principales: Zhou, Lin, Li, Jian, Tang, Yaping, Yang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789760/
https://www.ncbi.nlm.nih.gov/pubmed/33407563
http://dx.doi.org/10.1186/s12967-020-02648-7