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Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia

BACKGROUND: Chronic myelomonocytic leukemia (CMML) is an aggressive hematopoietic malignancy that arises from hematopoietic stem and progenitor cells (HSPCs). Patients with CMML are frequently treated with epigenetic therapeutic approaches, in particular the hypomethylating agents (HMAs), azacitidin...

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Detalles Bibliográficos
Autores principales: Berg, Johannes Lorenz, Perfler, Bianca, Hatzl, Stefan, Mayer, Marie-Christina, Wurm, Sonja, Uhl, Barbara, Reinisch, Andreas, Klymiuk, Ingeborg, Tierling, Sascha, Pregartner, Gudrun, Bachmaier, Gerhard, Berghold, Andrea, Geissler, Klaus, Pichler, Martin, Hoefler, Gerald, Strobl, Herbert, Wölfler, Albert, Sill, Heinz, Zebisch, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789782/
https://www.ncbi.nlm.nih.gov/pubmed/33407852
http://dx.doi.org/10.1186/s13148-020-00979-2