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Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) enable cardiotoxicity testing and personalized medicine. However, their maturity is of concern, including relatively depolarized resting membrane potential and more spontaneous activity compared with adult cardiomyocytes, implica...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789971/ https://www.ncbi.nlm.nih.gov/pubmed/32986966 http://dx.doi.org/10.1152/ajpheart.00148.2020 |