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Alcoholic hepatitis and metabolic disturbance in female mice: a more tractable model than Nrf2(−/−) animals

Alcoholic hepatitis (AH) is the dramatic acute presentation of alcoholic liver disease, with a 15% mortality rate within 28 days in severe cases. Research into AH has been hampered by the lack of effective and reproducible murine models that can be operated under different regulatory frameworks inte...

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Detalles Bibliográficos
Autores principales: Sheriff, Lozan, Khan, Reenam S., Saborano, Raquel, Wilkin, Richard, Luu, Nguyet-Thin, Gunther, Ulrich L., Hubscher, Stefan G., Newsome, Philip N., Lalor, Patricia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790192/
https://www.ncbi.nlm.nih.gov/pubmed/33067186
http://dx.doi.org/10.1242/dmm.046383