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TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response

Antiviral innate immune response to RNA virus infection is supported by Pattern-Recognition Receptors (PRR) including RIG-I-Like Receptors (RLR), which lead to type I interferons (IFNs) and IFN-stimulated genes (ISG) production. Upon sensing of viral RNA, the E3 ubiquitin ligase TNF Receptor-Associa...

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Detalles Bibliográficos
Autores principales: Khan, Kashif Aziz, Marineau, Alexandre, Doyon, Priscilla, Acevedo, Mariana, Durette, Étienne, Gingras, Anne-Claude, Servant, Marc J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790228/
https://www.ncbi.nlm.nih.gov/pubmed/33411856
http://dx.doi.org/10.1371/journal.ppat.1009111