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An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells

Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved. We designed an immunotoxin in which a single-chain...

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Detalles Bibliográficos
Autores principales: Cai, Yingyun, Yu, Shuiqing, Chi, Xiaoli, Radoshitzky, Sheli R., Kuhn, Jens H., Berger, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790382/
https://www.ncbi.nlm.nih.gov/pubmed/33411835
http://dx.doi.org/10.1371/journal.pone.0245024