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Predicting drug-metagenome interactions: Variation in the microbial β-glucuronidase level in the human gut metagenomes

Characterizing the gut microbiota in terms of their capacity to interfere with drug metabolism is necessary to achieve drug efficacy and safety. Although examples of drug-microbiome interactions are well-documented, little has been reported about a computational pipeline for systematically identifyi...

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Detalles Bibliográficos
Autores principales: Elmassry, Moamen M., Kim, Sunghwan, Busby, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790408/
https://www.ncbi.nlm.nih.gov/pubmed/33411719
http://dx.doi.org/10.1371/journal.pone.0244876