Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness

Insulin resistance (IR) precedes the development of type 2 diabetes (T2D) and increases cardiovascular disease risk. Although genome wide association studies (GWAS) have uncovered new loci associated with T2D, their contribution to explain the mechanisms leading to decreased insulin sensitivity has...

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Detalles Bibliográficos
Autores principales: Carcamo-Orive, Ivan, Henrion, Marc Y. R., Zhu, Kuixi, Beckmann, Noam D., Cundiff, Paige, Moein, Sara, Zhang, Zenan, Alamprese, Melissa, D’Souza, Sunita L., Wabitsch, Martin, Schadt, Eric E., Quertermous, Thomas, Knowles, Joshua W., Chang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790417/
https://www.ncbi.nlm.nih.gov/pubmed/33362275
http://dx.doi.org/10.1371/journal.pcbi.1008491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790417/
https://www.ncbi.nlm.nih.gov/pubmed/33362275
http://dx.doi.org/10.1371/journal.pcbi.1008491

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