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Dioscin Improves Pyroptosis in LPS-Induced Mice Mastitis by Activating AMPK/Nrf2 and Inhibiting the NF-κB Signaling Pathway

Dioscin, a natural steroid saponin, has been shown to have anti-inflammatory effects, but its protective mechanism against mastitis is still unknown. NLRP3 inflammasome and pyroptosis play important roles in the pathogenesis of many inflammatory diseases, including mastitis. The purpose of this stud...

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Detalles Bibliográficos
Autores principales: Ran, Xin, Zhang, Yan, Yang, Yuanxi, Hu, Guiqiu, Liu, Juxiong, Hou, Shuang, Guo, Wenjin, Kan, Xingchi, Fu, Shoupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790561/
https://www.ncbi.nlm.nih.gov/pubmed/33488936
http://dx.doi.org/10.1155/2020/8845521