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Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts: Insights from an agent-based model

Intestinal crypts are responsible for the total cell renewal of the lining of the intestines; this turnover is governed by the interplay between signalling pathways and the cell cycle. The role of Wnt signalling in cell proliferation and differentiation in the intestinal crypt has been extensively s...

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Detalles Bibliográficos
Autores principales: Ward, Daniel, Montes Olivas, Sandra, Fletcher, Alexander, Homer, Martin, Marucci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790739/
https://www.ncbi.nlm.nih.gov/pubmed/33489001
http://dx.doi.org/10.1016/j.csbj.2019.12.015