Snai1-induced partial epithelial–mesenchymal transition orchestrates p53–p21-mediated G2/M arrest in the progression of renal fibrosis via NF-κB-mediated inflammation

Renal fibrosis is the common feature of all progressive kidney diseases and exerts great burden on public health worldwide. The maladaptive repair mechanism of tubular epithelial cells, an important mediator of renal fibrogenesis, manifests with partial epithelial–mesenchymal transition (EMT) and ce...

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Detalles Bibliográficos
Autores principales: Qi, Ruochen, Wang, Jiyan, Jiang, Yamei, Qiu, Yue, Xu, Ming, Rong, Ruiming, Zhu, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790819/
https://www.ncbi.nlm.nih.gov/pubmed/33414422
http://dx.doi.org/10.1038/s41419-020-03322-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790819/
https://www.ncbi.nlm.nih.gov/pubmed/33414422
http://dx.doi.org/10.1038/s41419-020-03322-y

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